CRM Lists
Overview
These are also know as Customer Lists.
When creating an audience list, if your list has at least one PII attribute and no aggregated columns, it will be considered a CRM list.
These lists can be used to create segments based on different columns present on the lists.
More technical information
Unless a unique key is specified when creating the list - the first added PII attribute will be the unique key on that list.
If you specify another unique key, the PII attribute will be removed from the unique key and you will have to select the PII attribute as well if you want it as a unique key.